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View Vacancy -- PhD Studentships in Mammalian Genetics - MGU - 411

Open Date
05/01/2017 08:00
Close Date
07/02/2017 23:55
MRC Mammalian Genetics Unit

MRC Harwell is at the international forefront of the use of mouse genetics to study the relationship between genes and disease. The models we create and study are used to understand the disease processes that occur when a gene goes wrong.

Most human diseases have a significant genetic component - changes in the DNA of our genes contribute to the development of the disease. This is true for example for birth defects, diseases of childhood and chronic diseases such as diabetes, obesity, heart disease, stroke, respiratory and psychiatric conditions that affect people of all ages, nationalities and classes. Diseases of ageing such as Alzheimer’s and other neurodegenerative diseases are also a significant genetic burden on the human population.

MRC - Stipend
Didcot, Oxfordshire
£15,240 pa (Stipend)
PhD/DPhil registration fees at the University of Oxford
Fixed Term
Full Time
4 Year, PhD Studentship

The MRC Harwell Institute are offering 4 PhD studentships to study human disease using mouse genetics and mouse functional genomics. We have a variety of research areas that PhD students can select to complete their PhD. The training starts with a 3 month induction with training and laboratory rotations after which students decide which research area they want to complete their PhD in.

The MRC Harwell Institute is an International Centre for Mouse Genetics at the forefront of studies in mouse functional genomics and mouse models of human disease. We are engaged in lifetime studies, from developmental abnormalities through to diseases of ageing. The projects available incorporate a whole range of skills from genome editing, phenotyping, anatomy, histopathology, imaging, genomics, transcriptomics, proteomics, molecular biology, cell biology and cell culture. The research themes offering PhD projects at the MRC Harwell Institute for 2017 are:

  • Genetic basis of type 2 diabetes
  • Genetics of circadian rhythms and sleep in health and disease
  • The genetics and pathology of deafness
  • The role of cilia in development and disease
  • Disorders of sex development
  • Bioinformatics of mouse models of disease
  • Statistical genomics
  • Investigating novel stress response pathways in neurological disease
  • Novel and bespoke mouse models for dissecting neurodegenerative disease

Students are registered with the University of Oxford and the relevant department who will award the PhD. The studentship includes an annual stipend of £15,240 and University fees for students meeting the UK residence requirements detailed on our website. Currently we have 24 doctoral training students. Together with the postdoctoral fellows and other members of the Institute, our students contribute to a vibrant atmosphere providing a supportive environment for the development of future leaders in mouse genetics and the life sciences.

Residence requirements

The MRC studentships, provides students with a stipend and also pay PhD/DPhil registration fees at the University of Oxford. This funding is only available to candidates that meet the UK residence criteria as detailed in the Research Council UK (RCUK) conditions of research council training grants.

To be eligible for a full award (stipend and university fees) a student must have:

  • Settled status in the UK, meaning they have no restrictions on how long they can stay.
  • Been ‘ordinarily resident’ in the UK for three years prior to the start of the studentship. This means they must have been normally residing in the UK (apart from temporary or occasional absences).
  • Not been residing in the UK wholly or mainly for the purpose of full-time education. (This does not apply to UK or EU nationals).

Apply Now:

Candidates for an MRC-funded studentship must hold qualifications at the level of, or equivalent to a first-class or 2:1 honours’ degree in a biological science or related discipline.

To apply please complete the on-line application details and upload the following documents.

(1) One-page covering letter outlining your interest in doing a PhD in the MRC Harwell Institute

(2) CV with the names and contact details of two referees

Applications will only be eligible for consideration if all details are complete and both documents are uploaded.

Information about potential supervisors and research interests can be found on the research section of the MRC Harwell website


Informal inquiries can be made to the Director of Graduate Studies Professor Roger Cox by emailing


The MRC is a great place to work and progress your career, be it in scientific research or the support functions.

The MRC is a unique working environment where our researchers are rewarded by world class innovation and collaboration opportunities that the MRC name brings. The MRC is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including professional registration with the Science Council.

Choosing to come to work at the MRC means that you will have access to a whole host of benefits from a final salary pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme and childcare vouchers, as well as the chance to put the MRC on your CV in the future.


Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We welcome applications from all sections of the community irrespective of gender, race, ethnic or national origin, religion or belief, sexual orientation, disability or age. As "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy.


Final appointments will be subject to pre-employment screening.

This opportunity is closed to applications.