The London Institute of Medical Sciences (LMS) at HammersmithHospital is the third directly funded MRC research institute andenjoys close links with its partners at Imperial College and at theImperial College Healthcare NHS Trust. The LMS researchfocuses on strengthening the basic science underpinning ourunderstanding of human diseases and the translation of suchhigh quality research into a clinical setting.
Overall purpose:
The Chromatin & Development group, led by Dr Michelle Percharde, focuses on understanding the molecular events surrounding cell fate choices during early development. We aim to dissect novel transcriptional, epigenetic, and signalling axes important for embryogenesis. We are looking to recruit 1-2 enthusiastic, curious and highly-motivated scientists for UKRI-FLF and MRC funded positions within our recently established group.
Based on our recent research, a particular focus of the lab and the advertised 3-year postdoctoral position is to uncover how retrotransposons have been co-opted to regulate the earliest stages of mammalian development. The post-holder will be a key member of the Chromatin & Development group, and as such will enjoy a high level of scientific responsibility. They should have a strong background in chromatin, gene regulation and/or early development, and will be expected to be proactive in developing their research question within the group’s areas of interest and expertise.
We routinely use mouse embryonic stem cells (ESCs) and mouse embryos as models, adopting a combination of genome-wide techniques, CRISPR/Cas9 technology, high-resolution microscopy, biochemistry and molecular embryology approaches to probe gene and transposon function during development.
Main Responsibilities:
Person requirements
Education / Qualifications / Training required (will be
assessed from application form):
Essential:
Previous work experience required (will be assessed from
application form and at interview):
Desirable:
Knowledge and experience (will be assessed from
Personal skills/behaviours/qualities (will be assessed at
the interview):
*Salary quoted is inclusive of London weighting. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two, and £1,800 in the third year.
Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.
Please upload your CV, the names and contacts of two scientific references, along with a cover letter stating why you are suited for and specifically interested in this post (showing evidence against the requirements as per the Job Description and Person Specification). Please quote reference number LMS 1199.
The MRC is a unique working environment where scientific researchers and professional support staff can actively partake in world class innovation and collaboration opportunities and their skills and knowledge through accessing a wide catalogue of training & development, including professional registration with the Science Council.
In addition, MRC (part of UKRI) provides its community of employees access to a whole host of useful benefits, including a defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We warmly invite people from diverse backgrounds and heritage, including people who identify as having a disability, to apply for a role that excites them. As "Disability Confident" employers, we guarantee to interview all applicants who have disclosed they have a disability and who meet the minimum criteria for the vacancy.
UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs.
We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check. The role holder will be required to have the appropriate level of security screening/vetting required for the role. UKRI reserves the right to run or re-run security clearance as required during the course of employment.
This opportunity is closed to applications.