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View Vacancy -- MRC Postdoctoral Research Scientist LMS 2479
The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation, the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus (W12).
The LMS aims to deliver transdisciplinary team science, in synergistic interaction with Imperial College and the wider national research environment. Part of achieving this, is to recruit new talent and support postdoctoral scientists to become world leaders in their area of science.
Overall purpose:
A new opportunity has arisen for a 3 Year Postdoctoral Research Scientist to work in the Lymphocyte Development group headed by Professor Matthias Merkenschlager. This position is expected to be filled by the successful candidate from December 2024.
This project will focus X-linked competition, a newly discovered process by which X-chromosome sequence variation alters organismal development and skews the expression of X-linked sequence variants in a cell-type-specific manner (Buenaventura et al., 2024, Nature Genetics, published online 26th July, DOI 10.1038/s41588-024-01840-5). X-linked competition is unique to XX individuals and appears distinct from other known forms of cell competition that eliminate unfit cells from the developing organism
Main responsibilities:
- To plan and carry out research
- To write and publish the results
- To form good working relationships with other members of the group
- To assist others and co-supervise students when required
- To contribute to the development and maintenance of the group’s experimental or computational infrastructure as appropriate
Education / Qualifications / Training required (will be assessed from application form):
Essential:
- PhD or equivalent experience
Previous work experience required (will be assessed from application form and at interview):
Essential:
- Experience in human or mouse genetics, cell and molecular biology, human iPS / ES cell culture / differentiation or functional genomics is essential
Desirable:
- Expertise in the biology of cohesin / CTCF and computational skills would be a substantial advantage
Knowledge and experience (will be assessed from application form and at interview):
Essential:
- Ability to develop and apply new concepts
- Ability to independently carry out experimental and / or computational projects and analyses
- Creative approach to problem solving
- Good understanding of computational biology methods
- Great attention to details
- Good written communication skills in English
Personal skills / Behaviours / Qualities (will be assessed at the interview):
Essential:
- Ability to work independently and as part of a team and the ability to deal with a wide range of people
- Good oral communication skills in English
- Ability to constructively engage in scientific discussions
- Critical evaluation of data
This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successful applicant is likely to be eligible to apply. Immigration costs for applicant (100% visa and 100% Health Surcharge) and immediate dependents (100% visa and 50% health surcharge when applying with main applicant) can be reclaimed from LMS after taking up the post (terms and conditions apply).
Applicants should submit a CV, a brief cover letter describing scientific interests and names and contacts of two scientific references. Please quote reference number LMS 2479.
Applications without a supporting covering letter will not be considered.
The MRC is a unique working environment where scientific researchers and professional support staff can actively partake in world class innovation and collaboration opportunities and their skills and knowledge through accessing a wide catalogue of training & development, including professional registration with the Science Council.
In addition, MRC (part of UKRI) provides its community of employees access to a whole host of useful benefits, including a defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits
Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We warmly invite people from diverse backgrounds and heritage, including people who identify as having a disability, to apply for a role that excites them. As "Disability Confident" employers, we guarantee to interview all applicants who have disclosed they have a disability and who meet the minimum criteria for the vacancy.
UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs.
We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check. The role holder will be required to have the appropriate level of security screening/vetting required for the role. UKRI reserves the right to run or re-run security clearance as required during the course of employment.
This opportunity is closed to applications.