View Vacancy -- Research Support Officer - Structural Studies - Dr Kelly Nguyen - LMB 2081

Open Date
21/02/2023, 10:15
Close Date
21/03/2023, 23:55
MRC Laboratory of Molecular Biology

The MRC Laboratory of Molecular Biology (LMB) is one of the birthplaces of modern molecular biology and has played an important role in the development of many new techniques, most notably protein crystallography, cryo-electron microscopy, DNA sequencing and monoclonal antibodies. The LMB has a clear goal of understanding biological processes at the molecular level, with the ultimate aim of using this knowledge to tackle specific problems in human health and disease. We aim to tackle difficult, long-term problems, which often require investment over many years.

There are four scientific Divisions - Structural Studies, Protein and Nucleic Acid Chemistry, Cell Biology and Neurobiology. However, scientific collaboration between the different Divisions is extensive. Scientists are well supported by excellent scientific facilities and by the LMB Operations Group which maintains the core infrastructure and services of the institute.

The LMB provides an unsurpassed environment for both new and established researchers. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation.

UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at

MRC - 4
£32,005 to £40,769 per annum
Full Time

Overall purpose: 

To work within a programme aimed at structural and biochemical analysis of telomere maintenance in eukaryotic cells

Main duties/ Key responsibilities:

•    To undertake research aimed at deciphering the molecular details of telomere maintenance in mammalian cells 
•    To identify, develop and apply a broad range of techniques to pursue the research objectives
•    To contribute to lab-wide discussions and present work at lab meetings
•    To conribute to scientific papers and to the overall preparation of research for publication
•    To contribute to the LMB’s mission in the public engagement of science, and the translation of research findings into improvements in health care
•    To assist in the training of PhD students and other members of the LMB
•    Within the overall direction of the programme of the group and the remit of the project, and in discussion with the group leader, the post holder will make a significant input into determining the direction of the project. 
•    To plan their own work and objectives on a 12-month basis and will manage their experimental work within the project along with their supervisor.
•    To aid in the smooth running of the laboratory, i.e., arranging repair of broken machines. Make sure LMB Health and Safety rules are practiced in the lab.
•    To ensure the research is carried in accordance with good practice and in compliance with local polices and legal requirements.
•    To identify new equipment which will assist the group programme and to present argued cases for new purchases.

Working relationships: 

The postholder will report to Dr Kelly Nguyen and will interact and collaborate with other postdoctoral scientists, research support staff and students in the Group and across the LMB, and with external Groups as necessary.

Education / qualifications / training required: 
Essential: PhD in structural biology or similar

Desirable: Postdoctoral experience

Previous work experience required: 
Essential: Worked in a laboratory of high scientific standard with a well-respected international reputation.

Desirable: Written or co-written papers published in peer reviewed journals of high standard

Knowledge and experience: 
Essential: Structural biology, molecular biology, cloning, protein expression and purification, biochemistry

Desirable: Computational skills: cryo-EM and/or X-ray diffraction data collection and processing, protein structure solution and refinement, molecular graphics programs, Unix

Personal skills / behaviours / qualities: 
Essential: Is capable of working independently, but in collaboration with other members of the group. 

Desirable: Experience in mentoring students

The MRC is a great place to work and progress your career, be it in scientific research or the support functions.The MRC is a unique working environment where our researchers are rewarded by world class innovation and collaboration opportunities that the MRC name brings. The MRC is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including professional registration with the Science Council.

Choosing to come to work at the MRC (part of UKRI) means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, as well as the chance to put the MRC and UKRI on your CV in the future.

Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We welcome applications from all sections of the community irrespective of gender, race, ethnic or national origin, religion or belief, sexual orientation, disability or age. As "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy.

UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs.

We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check.  The role holder will be required to have the appropriate level of security screening/vetting required for the role.  UKRI reserves the right to run or re-run security clearance as required during the course of employment.

This opportunity is closed to applications.