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View Vacancy -- Post Doctoral Training Fellow - MGU - 649

Open Date
05/09/2017 09:30
Close Date
17/10/2017 23:55
MRC Mammalian Genetics Unit
MRC Harwell Institute is an international research centre at the forefront of mouse genetics. Located on the Harwell Campus, just south of Oxford, it is nestled amongst a vibrant community of leading science organisations. We aim o advance medicine through cutting-edge research into the genetic basis of disease. Our research programs span an entire lifetime, from embryonic development to diseases of ageing. They cover many areas, investigating the underlying genetics in disorders of sex development, the relationship between disrupted circadian rhythms and psychiatric disease, the role of cilia in development and disease, age-related deafness and otitis media, neurodegenerative disease and type 2 diabetes.
UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at

MRC - 4
Harwell Campus, Oxfordshire
£27,629 - £32,975
PDTF settlement and training allowances
Fixed Term
Full Time
4 years

We are seeking an outstanding postdoctoral researcher to work in a team investigating the molecular genetics of sexual development, led by Dr Andy Greenfield at the MRC Harwell Institute. You should be highly motivated, with an excellent understanding of genetics and an interest in using the mouse as a model system. You will drive research investigating genetic mechanisms causing disorders/differences of sex development by examining gene function during embryonic and fetal development in the mouse.

Research will involve a wide range of techniques, including mouse embryonic dissections, in situ hybridisation, RNA extraction and qPCR analysis of gene expression, studies on chromatin and epigenomics, microscopy/confocal imaging, cell and organ culture and the design of sophisticated mouse mutagenesis experiments, in addition to routine molecular techniques (DNA cloning, sequencing, genotyping etc).

The post is a MRC Postdoctoral Scientist. This role aims to support post-doctoral training and help establish successful research scientists in their chosen field. During the fellowship tenure, we are committed to provide mentorship for career development and improvement of communication skills.

Qualifications and Training:

PhD (or in the final stages of obtaining) in an appropriate discipline (e.g. Genetics, Biochemistry), or equivalent

Previous research experience required:

Hands-on experience in genetics research, preferably mouse genetics
Some experience in developmental biology/embryology is highly desirable
High motivation to pursue a career in academic science
The ability to work in a multi-disciplinary team and communicate complex scientific ideas to others

Personal skills/behaviours/qualities:

Pro-active and creative approach to meeting the demands of research
Excellent organisational skills and an ability to use the scientific literature to drive new experimentation
Excellent analytical skills

More information about the Mammalian Genetics Unit can be found at

The MRC is a great place to work and progress your career, be it in scientific research or the support functions.

The MRC is a unique working environment where our researchers are rewarded by world class innovation and collaboration opportunities that the MRC name brings. The MRC is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including professional registration with the Science Council.

Choosing to come to work at the MRC (part of UKRI) means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, as well as the chance to put the MRC and UKRI on your CV in the future.

Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We welcome applications from all sections of the community irrespective of gender, race, ethnic or national origin, religion or belief, sexual orientation, disability or age. As "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy.

Final appointments will be subject to pre-employment screening.

This opportunity is closed to applications.